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What is Tamoxifen (Nolvadex)?
Tamoxifen (brand name: Nolvadex) is a selective estrogen receptor modulator (SERM) used primarily for the treatment and prevention of hormone receptor-positive breast cancer. It works by blocking estrogen's effects on breast tissue, helping to slow or stop the growth of estrogen-dependent cancer cells.
Tamoxifen is also used off-label for other conditions related to hormone imbalances, including infertility treatment and gynecomastia in men.
- Generic name: tamoxifen citrate
- Brand name: Nolvadex
- Drug classes: Selective estrogen receptor modulators (SERMs)
Warnings
- Do not use tamoxifen if you are pregnant, as it may harm the fetus.
- Tamoxifen may increase the risk of blood clots, stroke, and endometrial cancer. Inform your doctor if you have a history of these conditions.
- Regular monitoring is required during tamoxifen treatment to check for side effects, such as uterine abnormalities or changes in liver function.
- Inform your healthcare provider if you are taking blood thinners, as tamoxifen may increase the risk of bleeding.
Before Using This Product
- Do not use tamoxifen if you are allergic to it or any of its components.
- Inform your healthcare provider if you have a history of blood clots, stroke, high cholesterol, or liver disease.
- Disclose any other medications or supplements you are taking, especially anticoagulants or hormonal therapies.
- Do not breastfeed while using tamoxifen.
How Should I Take Tamoxifen (Nolvadex)?
- Dosage: The typical dose ranges from 20 to 40 mg taken orally once daily or divided into two doses.
- With or Without Food: Tamoxifen can be taken with or without food.
- Duration: Treatment may last for 5 years or more, depending on the individual case and doctor's recommendation.
What Happens If I Miss a Dose?
- Take the missed dose as soon as you remember, unless it is close to the next scheduled dose.
- If it is almost time for the next dose, skip the missed dose and continue with your regular schedule.
- Do not double doses to make up for a missed dose.
What Happens If I Overdose?
- Symptoms of overdose may include dizziness, nausea, or vomiting.
- Seek emergency medical attention if you suspect an overdose.
What to Avoid
- Avoid using hormonal therapies or estrogen-containing products unless directed by your doctor.
- Avoid activities requiring full attention if you experience dizziness or fatigue while taking tamoxifen.
- Avoid alcohol consumption if it exacerbates side effects or interacts with your medication.
Tamoxifen Side Effects
Common side effects may include:
- Hot flashes
- Nausea
- Fatigue
- Vaginal discharge
- Leg cramps
Seek immediate medical attention if you experience severe or unusual symptoms, such as:
- Signs of blood clots, such as swelling, pain, or redness in the legs
- Sudden chest pain or shortness of breath
- Unusual vaginal bleeding
- Yellowing of the skin or eyes (jaundice)
- Severe allergic reactions, such as swelling of the face, lips, or tongue