What is Exemestane (Aromasin)?

Exemestane is an aromatase inhibitor used primarily in the treatment of breast cancer in postmenopausal women. It works by reducing the production of estrogen, which can fuel the growth of hormone-receptor-positive breast cancer cells.

Exemestane is often prescribed after other treatments, such as tamoxifen, to lower the risk of cancer recurrence. It is also used off-label in certain cases to manage other estrogen-dependent conditions.

• Generic name: exemestane
• Brand names: Aromasin
• Drug classes: Aromatase inhibitors, hormonal therapy agents

Warnings

• Exemestane is not suitable for premenopausal women unless prescribed in specific situations under medical supervision.
• It may decrease bone mineral density, increasing the risk of osteoporosis or fractures.
• Do not use exemestane during pregnancy, as it can harm the fetus.
• Exemestane may interact with other medications, such as estrogen-containing products or certain antidepressants. Inform your doctor of all current medications.

Before Using This Product

• Do not use exemestane if you are allergic to it or any of its components.
• Inform your doctor if you have osteoporosis, liver or kidney disease, or are pregnant or breastfeeding.
• Discuss any history of heart disease or high cholesterol with your healthcare provider.
• Avoid using exemestane if you are currently taking estrogen-containing products, as they may interfere with its efficacy.

How Should I Take Exemestane?

• Dosage: The usual dose is 25 mg once daily, typically after a meal.
• With Food: Exemestane should be taken after eating to improve absorption.
• Duration: Treatment duration varies based on the individual case but may extend up to 5 years or more.

What Happens If I Miss a Dose?

• Take the missed dose as soon as you remember, unless it is close to the next dose.
• If it is almost time for the next dose, skip the missed dose and resume your normal schedule.
• Do not double doses to make up for a missed dose.

What Happens If I Overdose?

• Symptoms of overdose may include dizziness, nausea, or other unusual effects.
• Seek emergency medical attention or contact a poison control center immediately if overdose symptoms occur.

What to Avoid

• Avoid using estrogen-containing products while taking exemestane, as they can reduce its effectiveness.
• Avoid heavy alcohol consumption, which may worsen bone density loss or liver function.
• Do not operate heavy machinery if you experience dizziness or fatigue while taking exemestane.

Exemestane Side Effects

Common side effects may include:

• Hot flashes
• Joint or muscle pain
• Fatigue
• Increased sweating
• Insomnia

Seek immediate medical attention if you experience severe or unusual symptoms, such as:

• Severe bone pain or fractures
• Chest pain or shortness of breath
• Signs of liver issues, such as yellowing of the skin or eyes (jaundice)
• Severe allergic reactions, such as swelling of the face, lips, or tongue