What is Anastrozole (Arimidex)?

Anastrozole (brand name: Arimidex) is a medication used primarily for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by reducing estrogen levels in the body to slow or stop the growth of estrogen-dependent cancer cells.

In some cases, anastrozole is used off-label to manage conditions related to hormone imbalance or to prevent estrogen-related side effects in individuals undergoing certain treatments.

• Generic name: anastrozole
• Brand name: Arimidex
• Drug classes: Aromatase inhibitors, hormonal therapy agents

Warnings

• Anastrozole is not recommended for premenopausal women unless prescribed under specific circumstances.
• Do not use anastrozole during pregnancy, as it may harm the fetus.
• Anastrozole may decrease bone mineral density, increasing the risk of osteoporosis or fractures.
• Inform your doctor if you have a history of heart disease, as anastrozole may increase the risk of cardiovascular events.

Before Using This Product

• Do not use anastrozole if you are allergic to it or any of its components.
• Inform your healthcare provider if you have osteoporosis, liver or kidney disease, or high cholesterol.
• Disclose any medications or supplements you are taking, as some may interact with anastrozole.
• Do not use anastrozole if you are pregnant or breastfeeding.

How Should I Take Anastrozole (Arimidex)?

• Dosage: The typical dose is 1 mg taken orally once daily.
• With or Without Food: Anastrozole can be taken with or without food.
• Duration: Treatment duration may vary, often prescribed for 5 years or more depending on the individual case.

What Happens If I Miss a Dose?

• Take the missed dose as soon as you remember, unless it is close to the next scheduled dose.
• If it is almost time for the next dose, skip the missed dose and continue with your regular schedule.
• Do not double doses to make up for a missed dose.

What Happens If I Overdose?

• Symptoms of overdose are uncommon but may include nausea, vomiting, or dizziness.
• Seek emergency medical attention if you suspect an overdose.

What to Avoid

• Avoid using estrogen-containing products, as they may interfere with the effectiveness of anastrozole.
• Avoid excessive alcohol consumption, which may worsen side effects like bone density loss or liver strain.
• Avoid driving or operating heavy machinery if you experience dizziness or fatigue while taking anastrozole.

Anastrozole Side Effects

Common side effects may include:

• Hot flashes
• Joint or muscle pain
• Fatigue
• Headache
• Bone pain

Seek immediate medical attention if you experience severe or unusual symptoms, such as:

• Severe chest pain or shortness of breath
• Swelling in the hands, feet, or legs
• Signs of liver problems, such as yellowing of the skin or eyes (jaundice)
• Severe allergic reactions, such as swelling of the face, lips, or tongue